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The herb milk thistle has been scientifically researched in Europe for over 45 years and today's herbalists believe it stimulates production of new liver cells and inhibits factors that may cause liver damage, like alcohol, drugs or environmental toxins. The active ingredient in milk thistle, silymarin, appears to act as an antioxidant and increases the concentration of glutathione in the cells. Glutathione is a substance that plays a role in detoxifying liver cells. Because both the liver and the skin are the organs most involved in toxin removal, many herbalists connect skin problems to faulty liver filtering.